The transformation of the energy system offers the transport sector opportunities to reduce primary energy consumption, increase efficiency, and lower greenhouse gas emissions. While battery-electric vehicles (BEVs) dominate light-duty vehicle electrification, challenges persist for freight and passenger transport over long distances due to battery weight and costs. Hydrogen from green electricity and e-fuels present gravimetric and economic advantages under specific conditions. This study conducts a bottom-up, simulation-based analysis of zero-emission powertrains, comparing BEVs and hybrid fuel cell electric vehicles. Results highlight their potential to reduce emissions, noise, and improve efficiency.